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Ownership Profile

Ownership Profile

Shareholder Breakdown

Shareholder Holders Value ($MM) % O/S Shares
Institution 47 24.09 120.10 4,219,916
Mutual Fund 14 0.73 3.52 123,841
Insider 1 0.27 1.36 47,653

Institutional Shareholder Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 15 15.90 80.88 2,841,888
Sellers 18 -2.27 10.34 -363,468
Net -- 13.63 70.54 2,478,420

Institutional Shareholder Concentration

Value ($MM) % O/S Shares
Total Inst. 24.09 120.10 4,219,916
Top 10 Inst. 23.17 115.77 4,067,667
Top 20 Inst. 23.91 119.25 4,189,969
Top 50 Inst. 24.09 120.10 4,219,916

Institutional Shareholder Style

Holders Value ($MM) % Inst Shares Shares
Growth 6 0.03 0.13 4,454
Core Growth 5 0.03 0.13 4,452
Growth 1 -- -- 2
Income 1 0.01 0.04 1,328
Income Value 1 0.01 0.04 1,328
Index 7 0.92 4.21 147,991
Other 15 17.65 88.65 3,114,891
Broker Dealer 6 0.07 0.30 10,670
GARP 2 0.02 0.10 3,454
Hedge Fund 6 1.91 8.58 301,343
VC/Private Equi 1 15.65 79.67 2,799,424
Value 3 0.17 0.79 27,777
Core Value 3 0.17 0.79 27,777

Top Holders: Institutional Investor

Holder Shares Held % O/S Share Change Filing Date
Care Capital, LLC 2,799,424 79.67 2,799,424 2/14/18
East Hill Management Company, LLC 265,040 7.54 -- 2/13/18
Krensavage Asset Management, LLC 255,412 7.27 -2,436 12/31/17
Finney Michael J 228,978 6.52 228,978 2/14/18
SC Fundamental, L.L.C. 169,831 4.83 -51,066 1/16/18
Renaissance Technologies LLC 122,264 3.48 13,765 12/31/17
Tucker (Sean N Ph.D.) 82,101 2.34 82,101 3/12/18
The Vanguard Group, Inc. 72,718 2.07 -18,713 12/31/17
BlackRock Institutional Trust Company, N.A. 43,448 1.24 107 12/31/17
Carlson Capital Management, LLC 28,451 0.81 14,225 3/31/18

* Insider values reflect direct beneficial ownership.

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